Found 18 matching trials
Safety, Tolerability and Efficacy of PfSPZ Vaccine Against Heterologous CHMI in US Malaria naïve Adults PHASE1 This is a randomized, double blind, placebo-controlled, single site, trial ...
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Fred Hutchinson Cancer Research Center
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Safety and Immunogenicity in Age De-Escalation of PfSPZ Vaccine in Tanzanian Adults, Children, and Infants PHASE1 The present trial will evaluate safety and tolerability as well as the vacc...
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Bagamoyo Research and Training center of the Ifakara Health Institute
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PfSPZ Challenge in Healthy Malaria-Naïve Adults in the United States PHASE1 This phase I trial of the replication-intact PfSPZ Challenge vaccine given ...
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Kaiser Permanente Washington Health Research Institute - Vaccines and Infectious Diseases
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Sanaria PfSPZ Challenge With Pyrimethamine or Chloroquine Chemoprophylaxis Vaccination (PfSPZ-CVac Approach): A Randomized Double Blind Placebo Controlled Phase I/II Trial to Determine Safety and Protective Efficacy Against Natural Plasmodium Falcipa... PHASE1 Background:
Malaria remains a major global health problem. Malaria is spre...
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Malaria Vaccine Center STTB/MRTC
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Regimen Optimization Trial of PfSPZ Vaccine in Equatorial Guinea PHASE1 This is a phase 1, randomized regimen optimization study of PfSPZ Vaccine i...
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Baney Clinical Research Center
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Trial to Evaluate the Safety, Immunogenicity and Protective Efficacy of Three or Five Administrations of GAP3KO Sporozoites PHASE1 This Phase 1 trial will include 16 subjects who will receive the Geneticall...
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Kaiser Permanente Washington Health Research Institute
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Optimization of Controlled Human Malarial Infection by Injection of P. Falciparum Sporozoites in Non-Immune Adults PHASE1 The study is designed to establish the best dose to safely infect healthy i...
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Centre d'Investigació del Medicament Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
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Chemoprophylaxis and Plasmodium Falciparum NF54 Sporozoite Immunization Challenged by Heterologous Infection NA Malaria, a disease caused by the parasite Plasmodium, is one of the world's...
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Radboud university medical center
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Safety and Efficacy of NF135 CPS Immunization NA This is an open label, randomized, controlled clinical trial. The primary a...
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Radboud university medical centre
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Study in Blood Stage Malaria Infection After DVI of Cryopreserved P. Falciparum (NF54 Strain) Sporozoites PHASE1 This is a single-centre, open-label, Phase Ib study designed to assess if i...
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SGS Belgium NV Clinical Pharmacology Unit
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